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Parkinome

2024 · Deep Learning, Bioinformatics, Explainability
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In this project, we developed deep learning architectures for Parkinson’s disease stratification across high-dimensional multi-omics datasets, achieving over 90% accuracy. The work was carried out during the first year of my master’s as a Machine Learning Research Assistant at Turku BioScience.

A central idea was leveraging the spatial inductive biases of convolutional neural networks on tabular biological data by investigating tabular-to-image transformations such as DeepInsight and IGTD. We also studied how explainability frameworks, e.g., SHAP, could aid in identifying candidate biomarkers subject to biological fidelity.

We presented a poster at the EDISS 2024 Winter School at Mälardalen University, Västerås, Sweden.